Health is a basic requirement to improve the quality of life. Professionalism is a set of attitude and behaviors which we have come to expect from individuals during the practice of their profession.  Professionalism is at the heart of doctors' relationships with patients and the public. But now a day those who are engaged in delivering health service to common people are practiced commercialization in their service. Lack of their professional attitude, ethical standard and altruism service common people of the country are suffered and the programs of government towards ensuring better health service are not fulfilled properly. This descriptive study has conducted on Sylhet Osmani Medicale College and Hospital. The objective of the study was to explore the nature and limitations of professionalism in Sylhet Osmani Medicale College. Among 100 respondents 50 were doctors, nurse and clinical pathologist and 50 were health service consumer or patient. The study has used the survey method following mixed approach. This study found that professionalism is not yet build up in Osmani Medicale College. Patients are not satisfied with doctors and hospital administration. This study specifically identified some problems in the way to practices professionalism. They are lack of man power, lack of modern technology, lack of morality and ethics, overburden with duties, lack of proper training etc. This study also recommended medical professional should have the adequate professional knowledge, proper training, morality and commitment to the profession.  Thus a positive and trustworthy relation may ensure better health service in Bangladesh.